2022
Millar CL, Anto L, Garcia C, Kim MB, Jain A, Provatas AA, Clark RB, Lee JY, Nichols FC, Blesso CN. Gut Microbiome-Derived Glycine Lipids Are Diet-Dependent Modulators of Hepatic Injury and Atherosclerosis. J Lipid Res. 2022 Mar 9:100192. doi: 10.1016/j.jlr.2022.100192. Online ahead of print. PMID: 35278409
Davi SM, Ahn A, White TA, Butterfield TA, Kwon OS*, Lepley LK*. The role of mitochondrial dysfunction and redox disturbances after non-invasive anterior cruciate ligament injury. (Frontiers Physiology - in press) (*Co-corresponding author)
Li, M-.B. Kim, Y.-K. Park, J.-Y. Lee. Fucoxanthin metabolites exert anti-fibrogenic and antioxidant effects in hepatic stellate cells. J Ag Food Res 2022; (In press). epub ahead of print on Nov 24, 2021. doi.org/10.1016/j.jafr.2021.100245
Chang Y, Funk M, Roy S, Stephenson E, Choi S, Kojouharov H, Chen B, Pan Z. Developing A Mathematical Model of Intracellular Calcium Dynamics for Evaluating Combined Anticancer Effects of Afatinib and RP4010 in Esophageal Cancer. Int J Mol Sci 2022; 23(3) 1763. doi.org/10.3390/ijms23031763
Kang, M-.B. Kim, Y-.K. Park, J-.Y. Lee. A mouse model of the regression of alcoholic hepatitis: Monitoring the regression of hepatic steatosis, inflammation, oxidative stress, and NAD+ metabolism upon alcohol withdrawal. J Nutr Biochem 2022; 99:108852. epub ahead of print on Sept 21, 2021. doi.org/10.1016/j.jnutbio.2021.108852
Dhuri K#, Gaddam R#, Kim YR, Jacobs J, Kumar V, Li Q, Irani K, Bahal R*, Vikram A*. “γ peptide nucleic acid-based miR-122 inhibition rescues vascular endothelial dysfunction in mice fed a high-fat diet.” Journal of Medicinal Chemistry (Accepted), 2022. #Both authors contributed equally, *co-corresponding senior authors
2021
Li, Y., Sun, J., Xu, T., Weng, X., Zhang, Y., Rasmussen, T.P., Dai., B. (2021) Efficient and rapid generation of neural stem cells by direct conversion of fibroblasts with a single microRNA. bioRxiv doi: https://doi.org/10.1101/2021.08.09.452601
Zhang, M. M., Bahal, R., Rasmussen, T. P., Manautou, J. E., Zhong, X.B. (2021) The growth of siRNA-based therapeutics: updated clinical studies. Biochemical Pharmacology 189:114432. PMID: 33513339
Prabhakar, B., Lee, S.W., Bochanis, A., Manautou, J., and Rasmussen, T.P. (2021) lnc-RHL, a novel long noncoding RNA required for the differentiation and survival of hepatocytes from human bipotent progenitor cells. Cell Proliferation 54(2):e12978.doi: 10.1111/cpr.12978 PMID: 33393114
Rasmussen, T. (2021) Reviewed Work: Epigenetics, Nuclear Organization and Gene Function: with implications of epigenetic regulation and genetic architecture for human development and health. John C Luchessi, author (2021). Quarterly Review of Biology, 96: 1, p. 54. University of Chicago Press. https://doi.org/10.1086/713236
McCabe, E.M., and Rasmussen, TP. (2021) lncRNA involvement in cancer stem cell function and epithelial-mesenchymal transitions. Seminars in Cancer Biology, 75: 38-48. doi: 10.1016/j.semcancer.2020.12.012. PMID: 33346133
Bruno RS, Pokala A, Torres-Gonzalez M, Blesso CN. Cardiometabolic health benefits of dairy-milk polar lipids. Nutr Rev. 2021 Dec 8;79(Supplement_2):16-35. doi: 10.1093/nutrit/nuab085. PMID: 34879146.
Garcia C, Blesso CN. Antioxidant properties of anthocyanins and their mechanism of action in atherosclerosis. Free Radic Biol Med. 2021 Aug 20;172:152-166. doi: 10.1016/j.freeradbiomed.2021.05.040. Epub 2021 Jun 1. PMID: 34087429.
Zhang MM, Bahal R, Rasmussen TP, Manautou JE, Zhong XB. The growth of siRNA-based therapeutics: updated clinical studies. Biochem Pharmacol, 2021, 189:114432. PMID: 33513339. PMCID: PMC8187268. DOI: 10.1016/j.bcp.2021.11443.
Wang P, Chen S, Wang Y, Wang X, Yan L, Yang K, Zhong XB, Han S, and Zhang L. The long non-coding RNA hepatocyte nuclear factor 4a antisense RNA 1 negatively regulates cytochrome P450 enzymes in Huh7 cells via histone modifications. Drug Metab Dispos., 2021, 49(5):361-368. PMID: 33674270. DOI: 10.1124/dmd.120.000316.
Bao Y, Phan M, Zhu J, Ma X, Manautou JE, and Zhong XB. Alterations of cytochrome P450-mediated drug metabolism during liver recovery and regeneration after acetaminophen-induced liver injury in mice. Drug Metab Dispos, 2021. PMID: 34348940. DOI: 10.1124/dmd.121.000459.
Migliorati J, Zhong XB. Spotlight: Mutations in muscle-type creatine kinase impact HIV prevention. Trends Pharmacol Sci, 2022, PMID: 34887127. DOI: 10.1016/j.tips.2021.11. 00189.
Rizzolo D, Kong B, Piekos S, Chen L, Zhong XB, Lu J, Wang P, Ma X, Xie W, Zhu H, Yang Q, Li A, Wang H, Siemiatkowska AS, Kagan L, Guo GL. Effects of overexpression of fibroblast growth factor 15/19 on hepatic drug metabolizing enzymes. Drug Metab Dispos. 2021, DMD-AR-2021-000416. DOI: 10.1124/dmd.121.000416.
Wang X, Yu Y, Wang P, Yang K, Wang Y, Yan L, Ma X, Zhong XB, and Zhang L. Long noncoding RNAs hepatocyte nuclear factor 1a antisense RNA 1 and hepatocyte nuclear factor 4a antisense RNA 1 are involved in ritonavir-induced cytotoxicity through histone modifications in hepatoma cells. Drug Metab Dispos. 2021, DMD-AR-2021-000693. DOI: 10.1124/dmd.121. 000693.
C. Tan, T. X. Pham, Y. Lee, J-.Y. Lee, M. J. Balunas. Identification of apocarotenoids as chemical markers of anti-inflammatory activity for spirulina supplements. J Agr Food Chem 2021; 69:12674-12685. upub ahead of print on October 21, 2021. doi.org/10.1021/acs.jafc.1c03015
Kang, Y. Lee, M-.B. Kim, S. Hu, H. Jang, Y-.K. Park, J-.Y. Lee. The loss of histone deacetylase 4 in macrophages exacerbates hepatic and adipose tissue inflammation in male but not in female mice with diet-induced nonalcoholic steatohepatitis. J Pathology 2021; 255:319-329. epub ahead of print on July 19, 2021. doi.org/10.1002/path.5758
M-.B. Kim, Y. Lee, M. Bae, H. Kang, S. Hu, T. X. Pham, J-.Y. Lee, Y-.K. Park. Sugar kelp (Saccharina latissima) inhibits hepatic inflammation and fibrosis in a mouse model of diet-induced nonalcoholic steatohepatitis. J Nutr Biochem 2021; 97:108799. epub ahead of print on June 10, 2021. doi: 10.1016/j.jnutbio.2021.108799
Kang, Y-.K. Park. J-.Y. Lee. Nicotinamide riboside, an NAD+ precursor, attenuates inflammation and oxidative stress by activating sirtuin 1 in alcohol-stimulated macrophages. Lab Invest 2021; 101:1225-1237. epub ahead of print on April 12, 2021. doi: 10.1038/s41374-021-00599-1
S-.Y. Yu, M-.B. Kim, Y-.K. Park, M. Bar, H. Kang, S. Hu, T. X. Pham, R. Carpenter, J. Lee, O-.H. Lee, J-.Y. Lee, Y-.C. Kim. Anthocyanin-rich aronia berry extract mitigates high-fat and high-sucrose diet-induced adipose tissue inflammation by inhibiting NF-kB activation in macrophages. J Med Food 2021; 24:586-594. epub ahead of print on March 22, 2021. doi: 10.1089/jmf.2020.0127
M-.B. Kim, H. Kang, Y. Li, Y-.K. Park, J-.Y. Lee. Fucoxanthin inhibits lipopolysaccharide-induced inflammation and oxidative stress by activating nuclear factor E2-related factor 2 via the phosphatidylinositol 3-kinase/AKT pathway in macrophages. Eur J Nutr 2021; 60(6):3315-3324. epub ahead of print on February 17, 2021. doi: 10.1007/s00394-021-02509-z
Caceres, M-.B. Kim, M. Bae, T. X. Pham, Y. Lee, S. Hu, E. O’Neill, B. Kim, Y-.K. Park, J-.Y. Lee. The effect of cranberry consumption on lipid metabolism and inflammation in human apolipoprotein A-I transgenic mice fed a high fat and high cholesterol diet. Br J Nutr 2021; 126: 183-190. epub ahead of print on October 16, 2020. doi: 10.1017/S0007114520004080
J. Baek, B. Hammock, I. K. Hwang, Q. X. Li, N. Moustaid-Moussa, Y. Park, S. Safe, N. Suh, S. S. Yi, D. C. Zeldin, Q. Zhong, J. A. Bradbury, M. L. Edin, J. P. Graves, H. Y. Jung, Y. H. Jung, M-.B. Kim, W. Kim, J. Lee, H. Li, J-.S. Moon, I. D. Yoo, Y. Yue, J-.Y. Lee*, H. J. Han*. Natural products in the prevention of metabolic diseases: Lessons learned from the 20th Frontier Scientists Workshop. Nutrients 2021; 13:1881. *, Co-corresponding author. doi: 10.3390/nu13061881
Kang, Y-.K. Park. J-.Y. Lee. Inhibition of alcohol-induced inflammation and oxidative stress by astaxanthin is mediated by its opposite actions in the regulation of sirtuin 1 and histone deacetylase 4 in macrophages. BBA Mol Cell Biol of Lipids 2021; 1866:158838. epub ahead of print on October 13, 2020. (PMID: 33065288). doi: 10.1016/j.bbalip.2020.158838
C. Donepudi, Y. Lee, J-.Y. Lee, J. D. Schuetz, J. E. Manautou. Multidrug resistance-associated protein 4 (Mrp4) is a novel genetic factor in the pathogenesis of obesity and diabetes. FASEB J 2021; 35:e21304. doi: 10.1096/fj.202001299RR
Montalvo RN, Doerr V, Kwon OS, Talbert EE, Yoo JK, Hwang MH, Nguyen B, Christou DD, Kavazis AN, and Smuder AJ. Protection Against Doxorubicin-Induced Cardiac Dysfunction is Not Maintained Following Prolonged Autophagy Inhibition. International Journal of Molecular Sciences, 2020 Oct 30;21(21):8105 [PMID: 33143122]
Kithas AC, Broxterman RM, Trinity JD, Gifford JR, Kwon OS, Hydren JR, Nelson AD, Jessop JE, Bledsoe A, Morgan DE, and Richardson RS. Nitric oxide synthase inhibition with N(G)-monomethyl-L-arginine: Determining the window of effect in the human vasculature. Nitric Oxide, 2020 Nov 1;104-105:51-60. [PMID: 32979497]
Smuder AJ, Roberts BM, Wiggs MP, Kwon OS, Yoo JK, Christou DD, Fuller DD, Szeto HH, Judge AR. Pharmacological targeting of mitochondrial function and reactive oxygen species production prevents colon 26 cancer-induced cardiorespiratory muscle weakness. Oncotarget, 2020 Sep 22;11(38):3502-3514. [PMID: 33014286]
Berg OK, Kwon OS, Hureau TJ, Clifton HL, Thurston TS, Le Fur Y, Jeong EK, Trinity JD, Richardson RS, Wang E, Layec G. Skeletal muscle mitochondrial adaptations to maximal strength training in older adults. Journal of Gerontology A Biol Sci Medi Sci. 2020 Nov 13;75(12):2269-2277 [PMID: 32253421]
Park SH*, Kwon OS*, Park SY, Weavil JC, Hydren JR, Andtbacka RHI, Hyngstrom JR, and Richardson RS. Vasodilatory and vascular mitochondrial respiratory function with advancing age: evidence of a free radically medicated link in the human vasculature. (*Co-first author) American Journal of Physiology- Regulatory Integrative Comp Physiology, 2020 April 1;318(4):R701-711 [PMID: 32022597]
Doerr V, Montalvo RN, Kwon OS, Talbert EE, Hain BA, Houston FE, Smuder AJ. Prevention of doxorubicin-induced autophagy attenuates oxidative stress and skeletal muscle dysfunction. Antioxidants (Basel), 2020 Mar 23;9(3):263 [PMID: 32210013]
Resaz, R; Cangelosi, D; Segalerba, D; Morini, M; Uva, P; Bosco, MC; Banderali, G; Estrella, A; Wanner, C; Weinstein, DA; Sechi, A; Paci, S; Melis, D; Di Rocco, M; Lee, YM; Eva, A. Exosomal MicroRNAs as Potential Biomarkers of Hepatic Injury and Kidney Disease in Glycogen Storage Disease Type Ia Patients. International journal of molecular sciences. 2021 Dec 28;23(1):328.
Cho, J-H; Weinstein, DA; Lee, YM. Emerging roles of autophagy in hepatic tumorigenesis and therapeutic strategies in glycogen storage disease type Ia: a review. Journal of inherited metabolic disease. 2021 Jan;44(1):118-128.
Choi S, Sathe A, Mathé E, Xing C, Pan Z. Identification of a Putative Enhancer RNA for EGFR in Hyper-Accessible Regions in Esophageal Squamous Cell Carcinoma Cells by Analysis of Chromatin Accessibility Landscapes. Front Oncol 2021; 11: 724687. https://doi.org/10.3389/fonc.2021.724687
Malik S, Kumar V, Liu CH, Shih KC, Krueger S, Nieh MP, Bahal R. “Head on Comparison of Self- and Nano-Assemblies of Gamma Peptide Nucleic Acid Amphiphiles.” Advanced Functional Materials, 2021, 2109552.
Dhuri K, Gaddam RR, Vikram A, Slack FJ, Bahal R. “Therapeutic potential of chemically modified, synthetic, triplex peptide nucleic acid-based oncomiR inhibitors for cancer therapy.” Cancer Research, 2021, 81(22), 5613–24.
Wahane A*, Malik S*, Shih KC, Gaddam RR, Chen C, Liu Y, Nieh MP, Vikram A, Bahal R. “Dual-modality poly-L-histidine nanoparticles to deliver peptide nucleic acids and paclitaxel for in vivo cancer therapy.” ACS Applied Materials & Interfaces, 2021, 13(38), 45244–45258. *Both authors contributed equally.
Malik S, Saltzman WM, Bahal R. “Extracellular Vesicles Mediated Exocytosis of Antisense Peptide Nucleic Acids.” Molecular therapy-Nucleic Acids (in print), 2021, 25, 302-315.
Dhuri K, Vyas R, Blumenfeld L, Verma R, Bahal R. “Nanoparticle delivered anti-miR-141-3p for stroke therapy.” Cells, 2021, 10(5), 1011.
Zhang M, Bahal R, Rasmussen T, Manautou J, Zhong X. “The growth of siRNA-based therapeutics: Updated clinical studies.” Biochemical Pharmacology, 2021, 189, 114432.
2020
Malik, S., Gupta, A, Zhong, X, Rasmussen, T, Manautou, J., Bahal, R. (2020) Emerging Therapeutic Modalities against COVID-19. Pharmaceuticals 13 (8), 188. PMID: 32784499
Singh, S., Bahal, R., and Rasmussen, TP. (2020) Evidence that miR-152-3p is a positive regulator of SETDB1-mediated H3K9 histone methylation and serves as a toggle between histone and DNA methylation. Experimental Cell Research 395(2):112216. doi: 10.1016/j.yexcr.2020.112216 PMID: 32768498
Lee, S.W., Bochanis, A., and Rasmussen TP (2020). Pluripotent cells for the assessment of chemically-induced teratogenesis and developmental toxicology: in Engineering Strategies for Regenerative Medicine 243-258. (Elsevier) (London, U.K.).
DiBella M, Thomas MS, Alyousef H, Millar C, Blesso C, Malysheva O, Caudill MA, Fernandez ML. Choline Intake as Supplement or as a Component of Eggs Increases Plasma Choline and Reduces Interleukin-6 without Modifying Plasma Cholesterol in Participants with Metabolic Syndrome. Nutrients. 2020 Oct 13;12(10):3120. doi: 10.3390/nu12103120. PMID: 33066009.
Millar CL, Jiang C, Norris GH, Garcia C, Seibel S, Anto L, Lee JY, Blesso CN. Cow's milk polar lipids reduce atherogenic lipoprotein cholesterol, modulate gut microbiota and attenuate atherosclerosis development in LDL-receptor knockout mice fed a Western-type diet. J Nutr Biochem. 2020 May;79:108351. doi: 10.1016/j.jnutbio.2020.108351. Epub 2020 Jan 23. PMID: 32007663.
Anto L, Warykas SW, Torres-Gonzalez M, Blesso CN. Milk Polar Lipids: Underappreciated Lipids with Emerging Health Benefits. Nutrients. 2020 Apr 4;12(4):1001. doi: 10.3390/nu12041001. PMID: 32260440.
Hirahatake KM, Bruno RS, Bolling BW, Blesso C, Alexander LM, Adams SH. Dairy Foods and Dairy Fats: New Perspectives on Pathways Implicated in Cardiometabolic Health. Adv Nutr. 2020 Mar 1;11(2):266-279. doi: 10.1093/advances/nmz105. PMID: 31555799.
Howard EE, Pasiakos SM, Blesso CN, Fussell MA, Rodriguez NR. Divergent Roles of Inflammation in Skeletal Muscle Recovery From Injury. Front Physiol. 2020 Feb 13;11:87. doi: 10.3389/fphys.2020.00087. eCollection 2020. PMID: 32116792.
Wang P, Shao X, Bao Y, Zhu J, Chen L, Zhang L, Ma X, and Zhong XB. Impact of obese levels on the hepatic expression of nuclear receptors and drug-metabolizing enzymes in adult and offspring mice. Acta Pharm Sin B, 2020, 10(1):171-185. PMID: 31993314. PMCID: PMC6976990. DOI: 10.1016/j.apsb.2019.10.009.
Chen L, Wang P, Manautou JE, Zhong XB. Knockdown of long noncoding RNAs hepatocyte nuclear factor 1a antisense RNA 1 and hepatocyte nuclear factor 4a antisense RNA 1 alters acetaminophen-induced cytotoxicity in HepaRG cells. Mol Pharmacol, 2020, 97(4):278-286. PMID: 32029527. PMCID: PMC7045890. DOI: 10.1124/mol.119.118778.
Bao Y, Shao X, Wang P, Zhu J, Xiao J, Shi J, Zhang L, Zhu HJ, Ma X, Manautou JE, Zhong XB. Acetaminophen-induced liver injury alters expression and activities of cytochrome P450 enzymes in an age-dependent manner in mouse liver. Drug Metab Dispos, 2020, 48(5):326-336. PMID: 32094214. PMCID: PMC7153563. DOI: 10.1124/dmd.119.089557.
Chen L, Bao Y, Jiang S, Zhong XB. The roles of long noncoding RNAs HNF1a-AS1 and HNF4a-AS1 in drug metabolism and human diseases. Noncoding RNA, 2020, 6(2):24. PMID: 32599764. PMCID: PMC7345002. DOI: 10.3390/ncrna6020024.
Malik S, Gupta A, Zhong XB, Rasmussen TP, Manautou JE, Bahal R. A clinical update of therapeutic modalities against COVID-19. Pharmaceuticals, 2020, 13(8):E188. PMID: 32784499. PMCID: PMC7465781. DOI: 10.3390/ph13080188.
Pande P, Zhong XB, and Waren K*. Histone methyltransferase G9a regulates expression of nuclear receptors and cytochrome P450 enzymes in HepaRG cells at basal level and in fatty acid induced steatosis. Drug Metab Dispos, 2020, 48(12):1321-1329. PMID: 33077425. DOI: 10.1124/dmd.120.000195.
Kang, Y. Lee, M. Bae, Y-.K. Park, J-.Y. Lee. Astaxanthin inhibits alcohol-induced inflammation and oxidative stress in macrophages in a sirtuin 1-dependent manner. J Nutr Biochem 2020; 85:108477. epub ahead of print on August 12, 2020. (PMID: 32801029). doi: 10.1016/j.jnutbio.2020.108477
M-.B. Kim, Y. Lee, M. Bae, H. Kang, T.X. Pham, S. Hu, J-.Y. Lee, Y-.K Park. Comprehensive characterization of metabolic, inflammatory and fibrotic changes in a mouse model of non-alcoholic steatohepatitis. J Nutr Biochem 2020; 85:108463. epub ahead of print on July 10, 2020. doi: 10.1016/j.jnutbio.2020.108463
Hu, M. Bae, Y-.K. Park, J-.Y. Lee. n-3 PUFA inhibit TGFb1-induced pro-fibrogenic gene expression by ameliorating the repression of PPARg in hepatic stellate cells. J Nutr Biochem 2020; 85;108478. epub ahead of print on June 15, 2020. doi: 10.1016/j.jnutbio.2020.108452
Bae, Y. Lee, T. X. Pham, Y-.K. Park, S. Hu, J-.Y. Lee. Astaxanthin inhibits the reduction of glycolysis during the activation of hepatic stellate cells. Life Sci 2020; 256: 117926. epub ahead of print on June 12, 2020. doi: 10.1016/j.lfs.2020.117926
C. Donepudi, G. J. Smith, O. Aladeloku, Y. Lee, S. J. Toro, M. Phof, A. L. Slitt, J-.Y. Lee, J. D. Schuetz, L. Wang, J. E. Manautou. Lack of multidrug-resistance associated protein 4 prolongs partial hepatectomy-induced hepatic steatosis. Toxicol Sci 2020; 175:301-311. epub ahead of print on March 6, 2020. doi: 10.1093/toxsci/kfaa032
L. Miller, C. Jiang, G. H. Norris, C. Carcia, S. Seibel, L. Anto, J-.Y. Lee, C. N. Blesso. Cow’s milk polar lipids reduce atherogenic lipoprotein cholesterol, modulate gut microbiota, and attenuate atherosclerosis development in LDL-receptor knockout mice fed a Western-type diet. J Nutr Biochem 2020; 79: 108351. epub ahead of print on Jan 23, 2020. doi: 10.1016/j.jnutbio.2020.108351
Bae, M-.B. Kim, Y-.K. Park, J-.Y. Lee. Health benefits of fucoxanthin in the prevention of chronic disease. BBA Mol Cell Biol of Lipids 2020; 1865:158618. epub ahead of print on January 10, 2020. doi: 10.1016/j.bbalip.2020.158618
Hu, E-.H. Cho, J-.Y. Lee. Histone deacetylase 9: Its role in the pathogenesis of diabetes and other chronic diseases. Diabetes Metab J 2020; 44: 234-244. epub ahead of print on March 24, 2020. doi: 10.4093/dmj.2019.0243
Hu, S. Hu, E. Fleming, J-.Y. Lee, Y. Luo. Chitosan-Caseinate-Dextran Ternary Complex Nanoparticles for Potential Oral Delivery of Astaxanthin with Significantly Improved Bioactivity. Int J. Biol Macromole 2020; 151: 747-756. doi: 10.1016/j.ijbiomac.2020.02.170
Montalvo RN, Doerr V, Kwon OS, Talbert EE, Yoo JK, Hwang MH, Nguyen B, Christou DD, Kavazis AN, and Smuder AJ. Protection Against Doxorubicin-Induced Cardiac Dysfunction is Not Maintained Following Prolonged Autophagy Inhibition. International Journal of Molecular Sciences, 2020 Oct 30;21(21):8105 [PMID: 33143122]
Kithas AC, Broxterman RM, Trinity JD, Gifford JR, Kwon OS, Hydren JR, Nelson AD, Jessop JE, Bledsoe A, Morgan DE, and Richardson RS. Nitric oxide synthase inhibition with N(G)-monomethyl-L-arginine: Determining the window of effect in the human vasculature. Nitric Oxide, 2020 Nov 1;104-105:51-60. [PMID: 32979497]
Smuder AJ, Roberts BM, Wiggs MP, Kwon OS, Yoo JK, Christou DD, Fuller DD, Szeto HH, Judge AR. Pharmacological targeting of mitochondrial function and reactive oxygen species production prevents colon 26 cancer-induced cardiorespiratory muscle weakness. Oncotarget, 2020 Sep 22;11(38):3502-3514. [PMID: 33014286]
Berg OK, Kwon OS, Hureau TJ, Clifton HL, Thurston TS, Le Fur Y, Jeong EK, Trinity JD, Richardson RS, Wang E, Layec G. Skeletal muscle mitochondrial adaptations to maximal strength training in older adults. Journal of Gerontology A Biol Sci Medi Sci. 2020 Nov 13;75(12):2269-2277 [PMID: 32253421]
Park SH*, Kwon OS*, Park SY, Weavil JC, Hydren JR, Andtbacka RHI, Hyngstrom JR, and Richardson RS. Vasodilatory and vascular mitochondrial respiratory function with advancing age: evidence of a free radically medicated link in the human vasculature. (*Co-first author) American Journal of Physiology- Regulatory Integrative Comp Physiology, 2020 April 1;318(4):R701-711 [PMID: 32022597]
Doerr V, Montalvo RN, Kwon OS, Talbert EE, Hain BA, Houston FE, Smuder AJ. Prevention of doxorubicin-induced autophagy attenuates oxidative stress and skeletal muscle dysfunction. Antioxidants (Basel), 2020 Mar 23;9(3):263 [PMID: 32210013]
Malik S, Slack FJ, Bahal R. “Formulation of PLGA nanoparticles containing short cationic peptide nucleic acids.” MethodsX, 2020, 7, 101115.
Malik S, Lim J, Slack FJ, Braddock DT, Bahal R. “Next-generation miRNA inhibition using short anti-seed PNAs encapsulated in PLGA nanoparticles.” Journal of Controlled Release, 2020, 327, 406-419.
Malik S, Gupta A, Zhong X, Rasmussen T, Manautou J, Bahal R. “Emerging Therapeutic Modalities against COVID-19” Pharmaceuticals, 2020, 13(8), 188.
Supriya S, Bahal R, Rasmussen T. “Evidence that miR-152-3p is a positive regulator of SETDB1-mediated H3K9 histone methylation and serves as a toggle between histone and DNA methylation.” Experimental Cell Research, 2020, 395(2), 112216.
Dhuri K, Bechtold C, Quijano E, Pham H, Gupta A , Vikram A, Bahal R. “Antisense Oligonucleotides: An Emerging area in Drug Discovery and Development.” Journal of Clinical Medicine, 2020, 9(6), 2004.
Wahane A, Waghmode A, Kapphahn A, Dhuri K, Gupta A, Bahal R. “Role of Lipid-Based and Polymer-Based Non-Viral Vectors in Nucleic Acid Delivery for Next-Generation Gene Therapy.” Molecules, 2020, 25(12), 2866.
Gaddam R, Veronica P, Kim YR, Gabani M, Jacobs J, Dhuri K, Kumar S, Kassan M, Li Q, Bahal R, Roghair R, Irani K, Vikram A. “Microbiota-governed microRNA-204 impairs endothelial function and blood pressure decline during inactivity in db/db mice.” Nature Scientific Reports, 2020, 10, 10065.
Kaplan A, Pham H, Liu Y, Oyaghire S, Bahal R, Engelman D, Glazer P. “Tumor-selective targeting of Ku80 for radiosensitization using a pH-sensitive peptide-PNA conjugate.” Molecular Cancer Research, 2020, 18(6), 873-882.
Chen L, Wang P, Bahal R, Manautou JE, Zhong X-b. “Ontogenic mRNA expression of RNA modification writers, erasers, and readers in mouse liver.” PLoS ONE, 2020, 14(12), e0227102.
Svoronos AA, Bahal R, Pereira MC, Barrera FN, Deacon JC, Bosenberg M, DiMaio D, Glazer PM, and Engelman DM. “Tumor-Targeted, Cytoplasmic Delivery of Large, Polar Molecules using a pH-Low Insertion Peptide.” Molecular Pharmaceutics, 2020, 17(2), 461–471.
Jeon, EH; Park, TS; Jang, Y; Hwang, E; Kim, S-J; Song, K-D; Weinstein, DA; Lee, YM; Park, B-C; Jun, HS. Glucose-6-phosphate transporter mediates macrophage proliferation and functions by regulating glycolysis and mitochondrial respiration. Biochemical and biophysical research communications. 2020 Mar 26;524(1):89-95.
Andersen CJ, Dupree L, Murray K, Ragonesi N, McMullen K, Cintron-Rivera L, and Doerr, A. Low-Density Lipoproteins, High-Density Lipoproteins (HDL), and HDL-Associated Proteins Differentially Modulate Chronic Myelogenous Leukemia Cell Viability. Lipids, 2020; 55(6): 615-626.